Nachlese: 3rd European DOE User Meeting

3rd European DOE User Meeting
Vom 01.06.2010 bis 02.06.2010 fand in Luzern das mittlerweile 3. European DOE User Meeting statt. 6 Keynote Speaker und 8 Vortragende aus Forschung und Industrie berichteten über neueste Enwicklungen und den praktischen Umgang mit Desing of Experiments. Dem freien Meinungs- und Erfahrungsaustausch wurde auch im offiziellen Tagungsprogramm mit 2 offenen Diskussionsrunden mit internationalen DOE-Experten der Firmen Stat-Ease (den Machern der Software Design Expert), CQ Consultancy (Belgien) und STACON (Deutschland) Raum gegeben. Zum Rahmenprogramm der Konferenz gehörten auch 3 Workshops, die mit großem Gewinn besucht wurden.
Eine äußerst angenehme und inspirierende Atmosphäre bot dabei das moderne Tagungshotel Astoria in Luzern. Einige Fotos vom Meeting finden Sie hier auf der Homepage von Stat-Ease.

Unter den Punkten Session 1 - 4 steht für die meisten, der in englischer Sprache gehaltenen Vorträge ein Volltext-Download in Form eines PDF-Dokuments zur Verfügung.


Programm

Session 1. (1. Juni 2010) – Chair: Ivan Langhans

Time Subject Speaker Abstract Full text
9:50 Welcome      
10:00 Size your design for Success Pat Whitcomb
(Stat-Ease, Inc.)
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10:50 Case Study 1:
Virus concentration
Hans de Hoog
(Intervet / Schering-Plough)
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11:15 Coffee break      
11:30 Case Study 2:
Use of DoE in Biopharmaceutical Industry
Alain Poncin
(ProtAffin)
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11:55 "State-of-the-Art Software Tools for DOE" Mark Anderson
(Stat-Ease, Inc.)
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12:20 Lunch      

Session 2. (1. Juni 2010) – Chair: Mark Anderson

Time Subject Speaker Abstract Full Text
14:00 Common mistakes in designing experiments Bertram Schäfer
(STACON)
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14:50 Case Study 4:
A successful real-life less standard application of Design of Experiments in the Research & Development department of AkzoNobel Car Refinishes:
Analyzing the influence of spraygun variations on the spraygun paint flow
Niels Dekker
(AkzoNobel Car Refinishes)
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15:15 Coffee break      
15:30 Case Study 5:
Mixture Optimisation in Practice – Using the Example of an Adhesive Formulation
Reto Dohner
(Sika Technology AG)
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15:55 Case Study 6:
Optimization of aggregated parameters
Dr. Pavel Nesladek
(Advanced Mask Technology Center)
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16:20 'Meet the consultant' – individual consulting sessions      
18:30 Conference Cruise Diner on Lake Lucerne      

Session 3. (2. Juni 2010) – Chair: Pat Whitcomb

Time Subject Speaker Abstract Full Text
9:00 Industrial strip-plot designs: design and analysis Peter Goos
(Uni of Antwerp)
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9:50 Screen, project and fold Bas van den Bogaert
(CQ Consultancy)
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10:30 Coffee break      
10:45 Case Study 7:
Response Surface Modelling and its application in supercritical fluid processes to support the conterminal land remediation technologies
M.N. Baig
(University of Birmingham)
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11:10 Case Study 8:
Effective planning of experimental approaches with knowledge matrices using a knowledge matrix for DOE preparation and documentation
Stefan Schurr
(Qualica)
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11:35 Case Study 9:
Applying DoE to the deposition of amorphous and microcrystalline silicon films by Hot-Wire CVD
Markus Höfer
(Fraunhofer Ist.)
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12:00 Lunch      

Session 4. (2. Juni 2010) – Chair: Bertram Schäfer

Time Subject Speaker Abstract Full Text
13:30 Correcting for multiple testing: old tricks and state-of-the-art solutions Ivan Langhans
(CQ Consultancy)
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16:20 'Meet the consultant' – Roundtable discussion with a panel of international DOE experts      
  Closing      

 

Optionale Workshops im Rahmen des 3rd European DOE User Meetings

Workshop DOE and RSM Simplified by Mark Anderson, Stat-Ease, Inc.


Workshop DOE and RSM Simplified

Im Rahmen des 3rd European DOE User Meetings werden insgesamt 3 optionale Workshops angeboten.

Termin

Das Workshop "DOE and RSM Simplified" by Mark Anderson, Stat-Ease, Inc. ist für den 31. Mai 2010, also einen Tag vor dem eigentlichen User Meeting terminiert.
 

Sprecher

Mark Anderson, Stat-EaseMark J. Anderson is a principal and general manager of Stat-Ease, Inc. Prior to joining the firm, he spearheaded an award-winning quality improvement program for an international manufacturer, generating millions of dollars in profit. Mark offers a diverse array of experience in process development, quality assurance, marketing, purchasing, and general management.
 


Agenda
 
Uhrzeit Thema
9:00 - 16:00 DOE and RSM Simplified including Lunch
Titel: Process Improvement via Design of Experiments for Screening and Respons Surface Methods Optimization

 
Abstract
 
DOE/RSM Simplified – Process Improvement via Design of Experiments for Screening and Response Surface Methods Optimization

This workshop offers an overview of design of experiments (DOE) and response surface methods (RSM). It illustrates an array of practical statistical tools for design and analysis of experiments aimed at breakthrough improvement and process optimization. Although this workshop is not a substitute for hands-on computer-intensive training, it will give participants a foundation for upgrading their DOE/RSM skills to a superior level.

The morning session introduces basic concepts of DOE and then explores full factorials, interactions, fractional factorials, and aliasing. Several informative case studies will be presented in detail. The afternoon session progresses into response surface methods (RSM). Once again, the material will be presented in case-study format that translates these statistical tools most effectively. During this session, participants will learn to appreciate all that RSM can do to find their sweet spot -- the ideal settings for the critical process factors.

Workshop Formulations Simplified by Pat Whitcomb, Stat-Ease, Inc.


Workshop Formulations Simplified

Im Rahmen des 3rd European DOE User Meetings werden insgesamt 3 optionale Workshops angeboten.

Termin

Das Workshop "Formulations Simplified" by Pat Whitcomb, Stat-Ease, Inc. ist für den 31. Mai 2010, also einen Tag vor dem eigentlichen User Meeting terminiert.
 

Sprecher

Pat Whitcomb, Stat-EasePat J. Whitcomb is the founding principal and president of Stat-Ease, Inc.. He co-authored Design-Ease software and Design-Expert software. He provided consulting on the application of design of experiments (DOE) and other statistical methods for mor than two decades. In addition, he is co-author of the books e.g. "DOE Simplified: Practical Tools for Effective Experimentation".
 


Agenda
 
Uhrzeit Thema
9:00 - 16:00 Formulations Simplified including Lunch
Titel: The Recipe of Success

 
Abstract
 
Formulations Simplified – The Recipe for Success

If you do product formulation, then standard factorial and response surface designs just don't work. You need to use mixture designs to ensure success. The one-day Formulations Simplified workshop teaches you how to effectively create mixture designs for a variety of problems. Develop statistical models of product performance. Then use response surface methods to identify the "sweet spot" where the optimum tradeoffs among multiple responses occur.

Ingredients for Efficient Experimentation

See the outline below for a list of topics you'll be introduced to in the Formulations Simplified workshop:

Section 1 – Introduction to Mixtures
  • What makes a mixture?
  • Mixture (Scheffé) polynomials
  • Simplex lattice designs
  • Synthetic medium case study
Section 2 – Constrained Mixtures, Simplex
  • Detergent formulation case study
    • Coding: Actual, Real, L_Pseudo
  • Optimization of multiple responses
    • Numerical (desirability function)
    • Graphical (overlay plot)
Section 3 – Constrained Mixtures, Non-Simplex
  • Sizing for precision
  • Constrained mixtures, extreme vertices
    • Shampoo case study
  • Optimal point selection
    • Flare case study
Section 4 – Advanced Topics
  • Multicomponent constraints
    • Fruit punch case study
  • Mixture amount experiments
    • Ibuprofen case study
  • DOE support

Workshop Multivariate Data Analysis in a DOE context by Ivan Langhans, CQ Consultancy


Workshop Multivariate Analysis

Im Rahmen des 3rd European DOE User Meetings werden insgesamt 3 optionale Workshops angeboten.

Termin

Das Workshop "Multivariate Data Analysis in a DOE context" by Ivan Langhans, CQ Consultancy ist für den 03.Juni 2010, also einen Tag nach dem eigentlichen User Meeting terminiert.
 

Sprecher

Ivan Langhans, CQ ConsultancyIvan Langhans, PhD. Chemestry, M.Sc. Statistics, founder of CQ-Consultancy, the Belgian Chemometrics Society and B-Enbis, part-time researcher at the Faculty of Business and Economics of the KULeuven. His research interests ar model selection and model validation.
 


Agenda
 
Uhrzeit Thema
9:00 - 13:00 Titel: Multivariate Data Analysis in a DOE context

 
Abstract
 
Multivariate Data Analysis in a DOE context

Multivariate methods such as Principal Component Analysis (PCA) have been developed to deal with correlations between variables. In this workshop a brief introduction to Principal Component Analysis will be given, with two illustrations of its use and power in a DOE context.

Principal Properties Design

You may need to test different solvents, additives, catalysts, system configurations, …. In that case you’re dealing with so-called categorical variables. Since categorical variables with n levels can be considered as n-1 variables, the number of experimental runs needed in a design increases rapidly with the number of levels to be tested, and often we can’t test them all.

A typical example is the choice of solvents to be used. For this example a first step in Principal Properties Design is to describe the solvents by a set of quantitative properties that are related to what makes them different (e.g. polarity, mass, di-electric constant, …), which results in a set of ten to twenty highly correlated variables. The next step is then to perform a PCA and select a representative set of solvents based on the principal components that adequately describe the set of descriptors, i.e. the principal properties.

With Principal Properties Design the problem of multi-level categorical factors can be circumvented, and on top, we even get information about items / levels that have not been explicitly tested.

Multi-response problems

Text-book examples of design often consider studies with just one or two responses. In real life you may have dozens. Again PCA can reveal the correlation between all those responses which helps identifying outlying values and prove unattainable targets (e.g. low value for response Y1 combined with high values for Y2 when they exhibit strong positive correlation).



Tagungsort

Hotel ASTORIA, LuzernHotel Astoria
Pilatusstraße 29
6002 Luzern
Tel: +41 41 226 88 88
Fax: +41 41 226 88 90
E-Mail: info@astoria-luzern.ch
 

Das ASTORIA ist ein modernes Kongress-Hotel mit 250 Zimmern und 12 Tagungsräumen. Kennzeichen des 2008 spektakulär erweiterten Hotels ist seine Gletscherspalten nachempfundene Glasfassade. Das architektonische Meisterwerk mit seinen lichtdurchfluteten Zimmern und modernsten Tagungsräumen bietet ein angenehmes Ambiente für das DOE User Meeting.

Das ASTORIA gehört zu den attraktivsten Stadt­hotels der Schweiz.