Bücher Statistik

Applied Statistics in the Pharmaceutical Industry

 Applied Statistics in the Pharmaceutical Industry
Produktbeschreibung

Applied Statistics in the Pharmaceutical Industry

With Case Studies Using S-PLUS
Autoren: Steven P. Millard; Andreas Krause (Eds.)
Sprache: English
Verlag: Springer-Verlag New York
Reihe:
ISBN: 0-387-98814-9


The purpose of this book is to provide a general guide to statistical methods used in the pharmaceutical industry, and to illustrate how to use S-PLUS to implement these methods. Specifically, the goal is to: *Illustrate statistical applications in the pharmaceutical industry; *Illustrate how the statistical applications can be carried out using S-PLUS; *Illustrate why S-PLUS is a useful software package for carrying out these applications; *Discuss the results and implications of a particular application; The target audience for this book is very broad, including: *Graduate students in biostatistics; *Statisticians who are involved in the industry as research scientists, regulators, academics, and/or consultants who want to know more about how to use S-PLUS and learn about other sub-fields within the indsutry that they may not be familiar with; *Statisticians in other fields who want to know more about statistical applications in the pharmaceutical industry.


Aus dem Inhalt:
  • Introduction.
  • Analysis of Large Designed Experiments Using Trellis Graphics and Tree-Based Regression.
  • Using S-PLUS to Perform Sample Size Calculations.
  • Design and Analysis of Two-Period Cross-Over Trials.
  • Analysis of Pharmacokinetic Studies.
  • Patient Compliance and Its Impact on Steady State Pharmacokinetics.
  • Survival Analysis to Compare Two Treatments in a Large Phase III Trial.
  • Using S-PLUS and SAS for ANOVA and Contrasts.
  • Using S-PLUS to Construct Design-Based Permutation Tests for a Variety of Endpoints and Designs in Phase III Clinical Trials.
  • Graphical Presentation of Single Patient Results.
  • Using The Seattle Angine Questionnaire as a Primary Outcome in Clinical Trials.
  • Health Economics.
  • Statistical Methodology and S
  • PLUS Programming for the Evaluation of the Decimal Reduction Time of a Sterilization Process in Pharmaceutical Production.
  • Acceptance Sampling Using S-PLUS.


Buchkategorie: Monograph

Infotext: Each chapter illustrates a practical problem using data from actual studies
No competing book has this pharmaceutical focus or use S-PLUS in this manner


Klassifizierung:
  • Statistik in Biologie, Biomedizin, Medizin, Gesundheitswesen
  • Computer-Anwendungen in der Biologie


Hauptzielgruppe: Science

Bibliographie: 2001, XVIII, 513 pp. 131 figs., Hardcover

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