SigmaPlot helps you creating technical graphics fast and accurate in the highest quality. Both 2D graphs and 3D graphs are available. The data analysis and graphics package SigmaPlot addresses scientists and engineers who create accurate, high-resolution graphs and want to publish their research results. The wide range of graphic export options ensures the exchange and publication of the results and the insertion of SigmaPlot graphs into Microsoft Word or Microsoft PowerPoint documents.

Graph options such as technical axis scaling, multiple axes, automatic error bars, regression lines, nonlinear curve fitting or confidence intervals provide maximum flexibility in the visualisation of your research results. Furthermore, SigmaPlot comprises a wide range of statistical functions including enzyme kinetic and many other curve fits, method comparison Bland-Altman, Kaplan Meier, etc.

Use SigmaPlot also to analyze your data. The statistical consulting assistant guarantees an easy and precise application of extensive statistical tools for analyzing your scientific data. Benefit from more than 50 statistical functions! Again, you can use a wizard for selecting the "right" statistical analysis method.

**SigmaPlot at a glance:**

- Easy creation of high-resolution graphs
- Statistical tools for analyzing your scientific data
- Graphical export options for publishing your results
- Automation by macros for repetitive tasks
- Direct access from Microsoft Excel to SigmaPlot

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### GraphPad Prism 8

### Origin Pro 2019b

### DeltaGraph 7

## SigmaPlot - the Best Windows Graphing Package available today

## What can SigmaPlot do for you?

### Work Smarter with Sigmaplot

SigmaPlot is an easy-to-use technical graphing and data analysis software package for scientists and engineers who need to produce defensible research and create exact, publication-quality graphs for technical publications, presentations or the web. Work smarter, not harder, with the award-winning interface and intuitive wizard technology that revolutionizes what researchers can accomplish on their own with SigmaPlot 12.

### SigmaPlot software helps you quickly create exact graphs

SigmaPlot graphing software from SYSTAT takes you beyond simple spreadsheets to help you show off your work clearly and precisely. With SigmaPlot, you can produce high-quality graphs without spending hours in front of a computer. SigmaPlot offers seamless Microsoft Office integration, so you can easily access data from Microsoft Excel spreadsheets and present your results in Microsoft PowerPoint® presentations.

### Graphing software that makes data visualization easy

Graph creation starts with SigmaPlot's award-winning interface. Take advantage of industry-standard menu design, menu toolbars, right mouse button support and graph preferences. Select the graph type you want to create from the Graph Toolbar's easy-to-read icons. The interactive Graph Wizard leads you through every step of graph creation. You get compelling, publication-quality charts and graphs in no time. SigmaPlot offers more options for charting, modeling and graphing your technical data than any other graphics software package.

Compare and contrast trends in your data by creating multiple axes per graph, multiple graphs per page and multiple pages per worksheet. Accurately arrange multiple graphs on a page using built-in templates or your own page layouts with SigmaPlot's WYSIWYG page layout and zoom features.

### Customize every detail of your charts and graphs

SigmaPlot offers the flexibility to customize every detail of your graph. You can add axis breaks, standard or asymmetric error bars and symbols; change colors, fonts, line thickness and more. Double-click on any graph element to launch the Graph Properties dialog box. Modify your graph, chart or diagram further by pasting an equation, symbol, map, picture, illustration or other image into your presentation.

### Publish your charts and graphs anywhere

Create stunning slides, display your graphs in reports or further customize your graphs in drawing packages. Save graphs for publication in a technical journal, article or paper with SigmaPlot's wide range of graphic export options. Presenting and publishing your results has never been easier - or looked this good. Create customized reports with SigmaPlot's Report Editor or embed your graphs in any OLE container - word processors, Microsoft PowerPoint or graphics program. Just double click your graph to edit directly inside your document. Quickly send your high-resolution graphs online to share with others.

### Share high-quality graphs and data on the Web

Export your graphs as high-resolution, dynamic Web pages - not simple GIF or JPEG files. Viewers can explore data used to create graphs and zoom, pan or print images at full resolution directly from a Web Browser. Automatically generate active Web objects from your graphs or embed the objects within other Web pages.

## 21 CFR 11

21 CFR Part 11 is the United States Food and Drug Administration's (FDA) requirement for electronic record keeping. These are the rules under which an electronic document can be considered equivalent to a paper document. In part, this includes software validation, password protection of data and macros, time-stamped audit trail capability, and various password and security measures.

SigmaPlot already satisfies the requirement for in-house validation using manual testing. Also the macro language provides the mechanism for repeatable "hands-off" analysis of instrumentation data.

SigmaPlot from Version 9.0 and above have the capability of importing data and running SQL queries from various ODBC-compliant databases. The new version also offers the ability to password protect notebooks for submittal to the FDA or other Government agencies that require adherence to security guidelines

## Example Graphs

## Further Information:

## SigmaPlot 30-Day Trial Download

As scientists ourselves, we know the importance of being able to evaluate unrestricted software to ensure that it fits your specific needs. Our trial version is fully functional for 30 full days, giving you the opportunity to thoroughly evaluate our software.

# SigmaPlot System Requirements

### Hardware

#### Windows 7, Windows 8.x and Windows 10, Windows Vista:

- 2 GHz 32-bit (x86) or 64-bit (x64) Processor
- 2 GB of System Memory for 32-bit (x86)

- 300 MB of Available Hard Disk Space
- CD-ROM Drive or Internet Connection
- 800×600 SVGA/256 Color Display or better
- Internet Explorer Version 8 or better

### Software

- Windows XP, Windows Vista, Windows 7, Windows 8.x, Windows 10; Internet Explorer 6 or higher
- Office 2003 or higher (paste to Powerpoint Slide, Insert Graphs into Word and other macros)

# New Features in

SigmaPlot Version 14

Below are some of the many new features in SigmaPlot Version 14:

## New Graph Features

- Arrows with solid arrowheads
- Added a right mouse menu command for pasting copied graph primitives (arrow, box, etc.) on the page
- A common operation on a graph is to zoom in, make a modification and then zoom out. A toggle was added, Ctrl+3, between your current zoom level and 100%.
- Data sampling dropdown now shows the maximum number of rows in the column
- Mini-toolbars for left mouse selection may be turned off
- An Anti-aliasing button has been added to the Graph Page Tab, Format Group
- Improved user interface for the Color Schemes dialog
- The “Each Curve” option is automatically turned on when performing a linear regression on one plot
- Additional Plot Regression Statistics
- Improved access to result graphs following statistical analysis – obtained by right clicking either a statistical report or another result graph
- The scatter matrix graph, used to display results of some statistical tests such as correlation, has increased support from 10 variables previously up to 40 variables
- Graph Properties can now be obtained by right clicking a graph or plot
- Renamed the Linear Regression command in the Graph Analysis group of the Analysis tab to Plot Regression
- Text and special symbols options are now shown directly on the symbols dialog
- The Graph Additions Group Name has been changed to Manage Plots
- Multiple Result Graph Types May Now Be Simultaneously Selected from the Create Result Graph Dialog
- The default appearance of all Result Graphs has been improved
- Added TIFF gray scale export option for graphs and graph pages
- A Page Templates button has been added to the Format group of the Graph Page ribbon tab

## New Worksheet Features

- Sorting data in the worksheet now supports multiple key columns
- Coefficient of Variation and 90% Confidence Interval added to Column Statistics
- Formatted text can now be used in statistical analyses
- Custom Column Statistics Items and Order May Now be Specified
- Statistical procedures may now use data from over 4000 worksheet columns

## New Analysis Features

- The One-Way Frequency Tables method has been added
- The unpaired (aka 2-independent samples) t-test has been enhanced to provide options to test the equality of the populations means of the two groups without assuming equal variances (Welch’s t-test)
- Ctrl-A now selects all program lines in user defined transforms
- More nonlinear regression application examples have been added that can now be accessed from the Help menu
- Improvements to the transforms examples that can now be accessed from the Help menu
- Improvements to some ape (automatic parameter estimate) functions in the Transform Language
- The number of groups for computing dummy variables has been extended from 100 to 1000
- Increased the maximum character length of labels in statistical tables from 30 to 255
- Error Message and Partial Save Nonlinear Regression Improvements
- The User-Defined Transform and Regression Dialogs are Now Resizable and can be Saved
- Improved User Interface for the Quick Transforms dialog

## New Miscellaneous Features

- Unicode is now supported
- Automatic Updating is available within SigmaPlot to get the latest updates to features
- User settings are now preserved for new versions of SigmaPlot
- Added new ribbon layouts for different types of workflows
- The Export button is also on the Main button
- New Macro Method for Exporting any Graph Page Selection
- Added a Save All command to the Main Button
- Two New Macros Using Indexed Data for Graphing
- Sample Data Sets Available from Help
- New Macro Automation Method to Determine a Worksheet Column Length
- Added File Import and Import Database to the Main Button panel for more visible access
- Data Can Now be Extracted from a Result Graph

## Graph Features

**Arrows with Solid Arrowheads**

The solid arrowhead is much more aesthetic than an arrowhead consisting of intersecting lines.

**Right Mouse Graph Primitive Paste**

A graph primitive object can now be both copied and pasted from the right click menu. This saves editing steps. These objects include the graph, boxes, circles, arrows, lines and text.

**Toggle between Zoom Levels**

One of the goals of this release is to make some procedures simpler. This is one of them. You frequently zoom in to make fine modifications but then you want to zoom out to see the overall effect. A toggle Ctrl+3 has been added. It will toggle between your current zoom level and 100% enabling you to easily make the changes and then see the result.

**Data sampling dropdown now shows the maximum number of rows in the column**

Data sampling in Graph Properties allows you to select the “from, to, by” rows for your graph. It also shows a sampling of the data rows but not every row and, in particular, not necessarily the last row. The “to” label now shows the numerical length of the column. This is a small feature but may help the user by catching a mis-selected column and also help you select the “by” number of rows.

**Turn Off Left Mouse Selection Mini-toolbars**

Some users only want right mouse selection mini-toolbars. The Main Button, Options, Page has a new checkbox: “Show mini toolbars on selection”. If you turn this off, mini toolbars will not appear when you select (left mouse) an object on the Page, but will still appear if you right click.

**New Anti-aliasing Button**

Use of anti-aliasing will smooth lines on your graph. This presently exists but was somewhat hidden under a right click on the page. This new button on the ribbon makes the feature obvious.

**Improved User Interface for the Color Schemes Dialog**

An unnecessary mouse click was removed. The color scheme dialog is displayed immediately. This feature and the next are examples of removing unnecessary mouse clicks.

**“Each Curve” Option is Automatically Turned on when Performing a Linear Regression on One Plot**

It is enabled in the Plot Regression dialog. This saves one step for a commonly used procedure.

**Additional Plot Regression Statistics**

More statistics have been added to the results in the Plot Regression dialog that is used for polynomial fitting to graph data. The statistics include the model performance measures R2, Adjusted R2, Standard Error of the Estimate and the Akaike Information Criterion. These are in addition to the standard errors for parameters and confidence intervals for the parameters. A control has also been added to change the number of results decimal places.

**Improved Access to Result Graphs Following Statistical Analysis**

Result graphs following a statistical analysis can now be obtained by right clicking either a statistical report or the page outside another result graph as shown below.

**Scatter Matrix Graph Dimension is Increased to 40 Variables**

The scatter matrix result graphs have increased support to a maximum of 40 variables:

**Graph Properties Can Now Be Obtained by Right Clicking a Graph or Plot**

The Graph Properties panel can be obtained from the Home tab or by double clicking a graph or plot on a graph. To make this even more visible, Graph Properties can now be obtained by right clicking on a graph or plot.

**Renamed Linear Regression command in the Graph Analysis group of the Analysis tab to Plot Regression**

This is to emphasize that this regression is obtained from a plot on a graph and not from the worksheet. The name change is also made to the dialog and tool tip text.

**Text and Special Symbols Options are Now Shown Directly on the Symbols Dialog**

A Symbol Font button has been added to the Symbols dialog. This makes it easier to change the font and visualize directly what it will look like on the graph. A Special Symbols button has been added which contains 120 addition symbols.

**The Graph Additions Group Name Has Been Changed to Manage Plots**

For clarity, the name of the Graph Additions panel on the Graph Page tab has been changed to Manage Plots since this is what these functions do.

**Multiple Result Graph Types May Now be Simultaneously Selected from the Create Result Graph Dialog**

Multiple Result Graph types may be selected using the mouse left click. This enables the user to perform in one step what before required multiple dialog openings. The keyboard behavior of selecting one graph using the arrow keys has not changed.

**The Default Appearance of Result Graphs Improved**

The default Result Graph appearance has been improved by modifying graph attributes that include axis line thickness, tick mark thickness, plot line thickness and color schemes for lines, line styles, symbol size and symbol edge thickness. The various line thicknesses and color schemes have been set to visually pleasing values.

**Gray Scale TIFF Option Added**

A Gray Scale option has been added to TIFF RGB export (compressed or not).

**Added a Page Templates Button on the Graph Page Ribbon Tab**

Page templates are more easily accessible from the ribbon with a Templates button in the Format group of the Graph Page tab.

## Worksheet Features

**Sorting Data in the Worksheet Now Supports Multiple Key Columns**

Use the Sort feature from the Worksheet tab Edit group to sort using multiple key columns.

**Coefficient of Variation and 90% Confidence Interval added to Column Statistics**

Use the Worksheet tab and View group to select View Column Statistics (or press F6). The image below shows the addition of % CV and 90% Confidence.

**Formatted Text Can Now be Used in Statistical Analyses**

Three formatted “a”s and three formatted “b”s are entered into a worksheet to identify groups for a statistical test. The small square in the upper right corner of the worksheet indicates that that text is formatted. Then, in the example below, the formatted text in the graph is increased in size. SigmaPlot now recognizes formatted text for statistical tests as it did in the past for plain text. A graph using these two groups and the t-test report are shown below:

**Custom Column Statistics Items and Order May Now Be Specified**

Specific Column Statistics items may now be selected and their order specified. Do this from the Main button, Options, Worksheet tab, Statistics when a Column Statistics worksheet is the current window. The two list box interface is shown below:

## Analysis Features

**One-Way Frequency Tables Method**

The one-way frequency tables method is new. It is applicable to multiple worksheet columns. It computes the number of times independent variable values occur.

**Enhancement of the Unpaired T-test**

The unpaired (aka 2-independent samples) t-test has been enhanced to provide the option to test the equality of the population means of the two groups without assuming equal variances (Welch’s t-test).

**Improved T-test Reports**

The option of selecting P-values from either a two-tailed or a one-tailed t-test has been added. This simplifies the appearance of the report giving the most useful results. Text has been added to explain the possible use of Welch’s test: “Use the results of Welch’s test, where equal variances are not assumed, if the equality of the population variances of the two groups is in doubt.”

**More Nonlinear Regression Application Examples Added to Nonlin.jnb**

Nonlinear regression examples are found in Help, SigmaPlot Samples and Nonlinear Regression. The file is located in the Samples subfolder of the user’s profile folder.

**Improvements to the Transforms Examples Xfms.jnb**

Several new transforms have been added with example worksheets and graphs. In SigmaPlot 13, this file contained 25 transforms. Some of these have been removed because a corresponding macro gives better results, but several more were added, with descriptions, worksheets and graphs so that this file now contains 55 transforms. Also, this file is now copied to the user profile folder during installation and is accessible from the Help menu in SigmaPlot (Help, SigmaPlot Samples and Transforms).

**Improvements to Some Automatic Parameter Estimation Functions in the Transform Language**

APE functions are used by SigmaPlot’s nonlinear regression feature. They determine good starting values for the fitting function’s parameters. The ape functions for polynomial and rational polynomial functions have been improved to avoid ill-conditioned or singular solution for the parameter estimates. Also, for power users, the ape function and the polynomial function used together in a user-defined transform provide a quick way of doing Polynomial Regression.

**Number of Groups for Dummy Variables has been Extended From 100 to 1000**

This is for users who want to use dummy variables for coding categorical variables for specific procedures in SigmaPlot’s statistics, like logarithmic regression, or covariates for Cox regression and ANCOVA. The advanced user can also use them to extend SigmaPlot’s multi-factor ANOVA by again converting the categorical variables to dummy variables and using multi-linear regression (GLM). As an example of the number of dummy variables required, a 5x5x5 3-Way ANOVA requires 124 dummy variables to describe it as a regression model, which is done internally in SigmaPlot. The dummy variable interface has been used with multi-linear regression to verify examples of SigmaPlot’s ANOVA results, but this could not have been done for the ANOVA design above in the previous version of SigmaPlot since the old limit was 100 dummy variables.

**Error Message and Partial Save Nonlinear Regression Improvements**

Increased the types of nonlinear regression error messages reported when using the Function Edit dialog to create fit equations. The ability to save partially complete equations so that the user can return to them later for completion has been added.

**Improved the Histogram and Polynomial Transform Language Functions and the Exponential Operator to Handle the nth Root of Negative Numbers**

The Transform Language function histogram was modified to add an optional third argument whose default value is zero. If the value of this argument is zero, the function behaves as before, assigning data to a bucket whose value equals the bucket’s right edge. If the value of the argument is not zero, then data is assigned to a bucket if its value equals its left edge instead. The behavior with a non-zero argument is more conventional. The Transform Language function polynomial was modified to replace its method for evaluation to use the Horner algorithm which is faster and more accurate. Also increased the maximum degree of the polynomial you can evaluate to 1000.

**Added the ability to compute nth roots of negative numbers when n is an odd integer**

Before, this resulted in missing values. So, for example, (-8)^(1/3) or (-8)**(1/3) should now yield -2. Also, if you were to graph the equation y=x^(1/3) for negative values of x before this change, you would get nothing.

**User-Defined Transform and Regression Dialogs are Now Resizable**

The User-Defined transform dialog for defining transforms and the Function Edit dialog for defining regression models can now be resized and have their new sizes saved between sessions of SigmaPlot. This makes them more convenient to use by preventing frequent scrolling to make editing changes.

**Improved User Interface for the Quick Transforms Dialog**

Two Quick Transforms windows have been combined making the combined window much easier to handle. Additional transform functions were also added as buttons: median, nth, avg, choose, rgbcolor, runavg, fft, invfft, normdist, norminv, tdist, tinv, fdist and finv. Also, the constants “π“ and “e” were added.

## Miscellaneous Features

**Using Unicode Characters in the Worksheet on the Graph Page and in Reports**

Here is an example of Unicode Russian characters in the graph:

**User Settings are now Preserved for New Versions of SigmaPlot**

Every change that the user makes in SigmaPlot is saved as a setting (saved in the spwUserSettings.ini file). From SigmaPlot 14 on, a new version of SigmaPlot will use the previous file of settings so that the user will “see” SigmaPlot exactly as it was before.

**New Ribbon Layouts for Different Types of Workflows**

There are now four different ribbon layouts for users that have specific uses:

- Default
- Compact
- Graphing
- Analysis

A good example of using the new configurations to speed up the workflow is in the Compact configuration. Here, the Worksheet tab has both worksheet and analysis commands and the Graph tab has both graph creating and editing commands. This shows the power of the new configurations as it saves a lot of switching back and forth between tabs.

**Worksheet Tab**

**Graph Tab**

**Export Button is now also on the Main Button**

The user can use the Main button and not repeatedly return to the Home tab to export.

**New Macro Method for Exporting any Graph Page Selection**

A new macro method has been added for the Auto Graph Item data type called ExportGraph and is used to export any selection on a graph page to a file. The method has seven arguments. From left to right, the arguments are filename, image file format and dpi, color resolution in bits, selection flag, height and width. This is used for both writing macros and in macro recording when running the Graph Export Dialog.

**Added a Save All command to the Main Button**

You can now save all open notebooks with one click.

**Two New Macros Using Indexed Data for Graphing**

Two new macros have been added to Macro Data Sets.jnb and SigmaPlot Macro Library.jnb. These macros (Box Plot, Using Indexed Data, Error Bar Plots Using Indexed Data) show how indexed data is used in graphing, expanding what SigmaStat does in result graphs.

**Sample Data Sets Available from Help**

Help now has a SigmaPlot Samples item from which sample data sets can be opened. Notebooks for Graphs, Statistical Tests, Macro Data Sets, Transforms and Nonlinear Regression are available.

**New Macro Automation Method to Determine a Worksheet Column Length**

A new automation method has been added on the automation DataTable object given by long ColumnLength (long col). This method finds the length of a column defined from the first row to the last non-empty row. A return value of zero shows that the column is empty.

**Data Can Now be Extracted from a Result Graph More Easily**

Data for a Result Graph is contained internally and not in a worksheet. You can now extract the data from a Result Graph by selecting the Data button in the Navigate group of the Home tab. A Result Graph must be in focus. The tooltip for the Data button will say “View Graph Data.” A new section will be created with a worksheet containing the data. This allows extracting the data for a Result Graph and placing it into a worksheet.